outset• But at the outset there is always great harm.• I was fairly ignorant of Third World literature at the outset and in many respects still am.• Hennepin and La Salle, whose subsequent westward expedition he was to join, strucksparks off one another from the outset.• Recognising sharppractice in their dealers from the outset, they would be less likely to blame them for hugelosses.• Fourthly, from the outset it is important to be sure that there is agreement with the patient about what is planned.• Stanford used some physical play inside and the playmaking of point guard Brevin Knight to take the lead from the outset.• Prosecutorssuspected from the outset that Stoner had fled the country.