smallpox• Sadly the Archduchess died during a smallpoxepidemic before the wedding took place.• Edward Jenner developed a vaccine against smallpox.• They died in epidemics of yellowfever, cholera, and smallpox.• He had very fine, fair hair and pale skin, faintly pitted by smallpox.• Some progress was made upon a few, particularly the reduction of major epidemics of malaria, cholera, smallpox and yellow-fever.• A lover dying of smallpox - Miss Phoebe was scarred from it.• He was also blind in one eye, the result of a youthfulbout with smallpox.• On the way, the crew came down with smallpox.