irritable• Since Steve quitsmoking, he's been really irritable.• Zoe hadn't had much sleep and was feeling tired and irritable.• It made him angry and irritable.• In his cabin Stubb wonders what makes the Captain so irritable and restless.• She had always been irritable, even in sanity, when she could look after herself.• You're turning into an irritable old man.• Poor boy, she thought, away from his loving home and now dumped with an irritable old man.